Physiological inhibitors of coagulation in fulminant hepatic failure
- 1 June 1992
- journal article
- research article
- Published by Wolters Kluwer Health in Blood Coagulation & Fibrinolysis
- Vol. 3 (3) , 243-248
- https://doi.org/10.1097/00001721-199206000-00002
Abstract
To study the effect of the severe loss of hepatic synthetic function on the inhibitors of coagulation we have measured protein S (total and free), protein C, heparin cofactor II and antithrombin III in 30 patients with fulminant hepatic failure. The results showed severe reduction in all inhibitor levels with mean (± SE) values of: protein S, 0.26 ± 0.03 U/ml; protein C, 0.26 ± 0.03 U/ml; heparin cofactor II, 0.12 ± 0.02 U/ml and antithrombin III, 0.21 ± 0.02 U/ml. Heparin cofactor II was significantly lower than the other inhibitors (PKeywords
This publication has 0 references indexed in Scilit: