Seizure‐associated hippocampal volume loss: A longitudinal magnetic resonance study of temporal lobe epilepsy
- 23 April 2002
- journal article
- research article
- Published by Wiley in Annals of Neurology
- Vol. 51 (5) , 641-644
- https://doi.org/10.1002/ana.10171
Abstract
This longitudinal quantitative magnetic resonance imaging study of 24 patients with mild temporal lobe epilepsy shows an ipsilateral hippocampal volume decrease of 9% (range, −30 to +0.5%; p = 0.002, paired t test) over a period of 3.5 ± 0.7 years. The hippocampal volume loss was correlated to the number of generalized seizures between the scans (p = 0.0007, r = 0.6), suggesting seizure-associated hippocampal damage.Keywords
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