Paediatric aspects of the Aberdeen typhoid outbreak.

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Abstract
Eighty-six children were affected in the 1964 Aberdeen typhoid outbreak. The age and familial incidence and the clinical features of these cases are described and the difficulties of early diagnosis emphasized. The disease generally ran a mild course and there were few complications and no deaths. Chloramphenicol and ampicillin separately or in combination were given to all cases. Chloramphenicol was superior to ampicillin in the control of fever and early symptoms, but the clinical relapse rate was lower in those cases treated with ampicillin. Both drugs proved unsatisfactory in eliminating the organism from the stools: 48 children had positive stool cultures after conclusion of the 1st course of treatment.

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