IMMUNITY IN CATTLE TO BABESIA BOVIS AFTER SINGLE INFECTIONS WITH PARASITES OF VARIOUS ORIGIN
- 1 January 1979
- journal article
- Published by Wiley in Australian Veterinary Journal
- Vol. 55 (1) , 10-12
- https://doi.org/10.1111/j.1751-0813.1979.tb09535.x
Abstract
Sixty calves, 3 to 6 months old, were vaccinated once against Babesia bovis in groups of 10, by the following methods: (a) tick infestation; (b) inoculation of virulent parasites obtained from the tick-infested animals immediately after infection; (c) inoculation of the parasites used in (b) attenuated by passage through splenectomised calves; (d) inoculation of commercially-available, living, attenuated vaccine; (e) inoculation of virulent parasites obtained from the tick-infested animals in (a) one year after infection; (f) inoculation of the parasites used in (e) attenuated by passage. All vaccinated animals were maintained tick-free and were strongly immune to challenge with a heterologous strain of B. bovis approximately 4 years after vaccination. There was no difference in immunogenicity between any of the B. bovis populations.Keywords
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