GASEOUS EXCHANGE BETWEEN THE BLOOD AND THE LUMEN OF THE STOMACH AND INTESTINES

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Abstract
The course of changing concentration of CO2 in the cat''s stomach was followed as it approached equilibrium with the blood gases when the initial concentration of CO2 differed from the equilibrium value, and when the partial pressure of CO2 in the blood was varied abnormally. The exchange is strictly predictable from the laws of diffusion. Velocity with which equilibrium is reached and the value attained are independent of the direction of diffusion. The thickness of the membrane through which diffusion occurs was estimated from rates of exchange and diffusion coefficients of gases in tissue. Behavior of CO2, O2, N2, CH4, H2, H2S, and room air when introduced into the small intestine, rates of absorption, and the equilibrium established between them and blood gases were studied. Difference in absorption rate of the gases under normal conditions ranges from a rapid disappearance of CO2 to a relatively slight N2 absorption even after several hours. Partial obstruction of the portal vein causes marked rise in CO2 percentage and corresponding increase in total volume of gas in an intestinal loop.

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