Parkinsonism after Taking Ecstasy

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Abstract
Recreational use of 3,4-methylenedioxymethamphetamine (MDMA, or “ecstasy”), a hallucinogen, has increased both in Europe and the United States.1 This substance is manufactured in illicit laboratories from a variety of organic ketone precursors. MDMA, which is structurally related both to the stimulant amphetamine and to the hallucinogen mescaline, promotes the release of both serotonin and dopamine from synaptic terminals.2 We report a case of parkinsonism after repeated use of this drug.