Minor Histone 2A Variants and Ubiquinated Forms in the Native H2A:H2B Dimer
- 29 July 1983
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 221 (4609) , 468-470
- https://doi.org/10.1126/science.6306766
Abstract
Histone octamers from calf thymus were separated into (H3:H4)2 tetramers and H2A:H2B dimers by chromatography through Sephadex G100. The tetramers and dimers were analyzed for variants, ubiquitin adducts, and proteolyzed forms. The minor histone variants H2A.X and H2A.Z were found to be associated with histone H2B as H2A.X:H2B and H2A.Z:H2B dimers, respectively. Ubiquitin adducts of the H2A's and H2B were also present in H2A:H2B dimers.This publication has 13 references indexed in Scilit:
- Differential conservation of histone 2A variants between mammals and sea urchins.The Journal of cell biology, 1982
- Separation of basal histone synthesis from S-phase histone synthesis in dividing cellsCell, 1981
- Two-Dimensional Gel Analysis of Histones in Acid Extracts of Nuclei, Cells, and TissuesEuropean Journal of Biochemistry, 1980
- Histone 2A, a heteromorphous family of eight protein speciesBiochemistry, 1980
- Nucleosome StructureAnnual Review of Biochemistry, 1980
- The histone core complex: an octamer assembled by two sets of protein-protein interactionsBiochemistry, 1978
- Non-allelic variants of histones 2a, 2b and 3 in mammalsNature, 1977
- A chromatin-bound proteolytic activity with unique specificity for histone H2ACell, 1976
- Proteolytic degradation of histones and site of cleavage in histone F2a1 and F3FEBS Letters, 1975
- [103] Preparation and assay of deoxyribonucleic acid from animal tissuePublished by Elsevier ,1957