PREVENTION OF DEEP-VEIN THROMBOSIS IN UROLOGICAL PATIENTS - CONTROLLED, RANDOMIZED TRIAL OF LOW-DOSE HEPARIN AND EXTERNAL PNEUMATIC COMPRESSION BOOTS

  • 1 January 1978
    • journal article
    • research article
    • Vol. 83  (2) , 230-234
Abstract
A prospective, randomized clinical trial in 83 patients undergoing open urological operations was performed to compare the relative prophylactic efficacy of low-dose heparin and external pneumatic compression (EPC) of the calves in comparison to no treatment in the prevention of deep vein thrombosis (DVT). The diagnosis of DVT was established by the 125I fibrinogen scan and contrast phlebography. EPC apparently is more effective than no treatment (P < 0.04) and more effective than low-dose heparin (P < 0.04) in the prevention of DVT. There was one pulmonary embolus in each of the 3 groups, and in the treatment groups this occurred without evidence of DVT.

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