Cytotoxic Isoprenylated Flavans of Broussonetia kazinoki

Abstract
Two new prenylflavans [kazinols Q (1) and R (2)] and five known compounds [kazinols D (3), K (4), and H, 7,4‘-dihydroxyflavan (5), and oleanolic acid] were isolated from the root bark of Broussonetia kazinoki. The cytotoxic activity of 1−5 was evaluated against several different cell lines.