EVALUATION OF THE ROLE OF RADICAL-MASTECTOMY, POSTOPERATIVE RADIATION AND CHEMOTHERAPY IN PATIENTS WITH STAGE IIB-(T1-2N2MO) BREAST-CANCER

  • 1 January 1983
    • journal article
    • research article
    • Vol. 29  (9) , 85-91
Abstract
The 1st results of a joint study carried out at a number of oncological instutitions of the RSFSR [Russian SFSR, USSR] are presented. The role of Holstead''s radical operation, postoperative radiation and chemotherapy in patients with stage IIb (TI, 2NIMO) breast cancer was analyzed in 822 case histories. Recurrences and metastases were detected in 12.6% of surgical patients (regional.sbd.3.2%, distant metastases-in 9.4%). A slightly lower frequency of recurrences and metastases (11.4%) was recorded in group II (Holstead''s operation and postoperative radiation treatment). The lowest frequency was in group III: recurrences were 2.1 times less frequent than in study group 1 and 1.9 times less frequent than in group II. As for metastasis incidence, the figures were 2.2 and 2.1, respectively. The data obtained serve as a base for further development of joint studies on the use of combined therapy of stage IIb breast cancer including chemotherapy.