A swiss family with hemoglobin P Galveston 61-161-161-1, including two patients with Hb P/β thalassemia
- 1 August 1975
- journal article
- Published by Springer Nature in Annals of Hematology
- Vol. 31 (2) , 61-68
- https://doi.org/10.1007/bf01633721
Abstract
The mutant Hb P Galveston (β117His→Arg) is observed in two heterozygotes for β thalassemia and by itself does not cause clinical symptoms. Some of the physicochemical properties of Hb P Galveston are identical to the ones of hemoglobin Zürich (β63His→Arg) so that only a detailed analysis led to its proper identification. Das mutierte Hämoglobin Hb P Galveston (β117His→Arg) wird in zwei für β-Thalassämie heterozygote Patienten beschrieben. Es hat keine klinischen Symptome zur Folge. Einige physikalisch-chemische Eigenschaften von Hb P Galveston sind identisch mit denjenigen von Hb Zürich (β63His→Arg). Es war daher eine detaillierte Analyse zur richtigen Identifikation nötig.Keywords
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