Downregulation of urokinase plasminogen activator receptor expression inhibits Erk signalling with concomitant suppression of invasiveness due to loss of uPAR–β1 integrin complex in colon cancer cells
Open Access
- 15 July 2003
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 89 (2) , 374-384
- https://doi.org/10.1038/sj.bjc.6601098
Abstract
No abstract availableKeywords
This publication has 49 references indexed in Scilit:
- Direct integrin αvβ6-ERK binding: implications for tumour growthOncogene, 2002
- Integrin αvβ3/Vitronectin Interaction Affects Expression of the Urokinase System in Human Ovarian Cancer CellsPublished by Elsevier ,2001
- Urokinase/urokinase receptor and vitronectin/αvβ3 integrin induce chemotaxis and cytoskeleton reorganization through different signaling pathwaysOncogene, 2001
- Deregulation of the signaling pathways controlling urokinase productionEuropean Journal of Biochemistry, 1999
- Binding of Urokinase-type Plasminogen Activator to Its Receptor in MCF-7 Cells Activates Extracellular Signal-regulated Kinase 1 and 2 Which Is Required for Increased Cellular MotilityPublished by Elsevier ,1998
- Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors.The Journal of cell biology, 1996
- Requirement of Receptor-bound Urokinase-type Plasminogen Activator for Integrin αvβ5-directed Cell MigrationJournal of Biological Chemistry, 1996
- Regulation of Integrin Function by the Urokinase ReceptorScience, 1996
- Overexpression of urokinase receptor in breast cancer cells results in increased tumor invasion, growth and metastasisInternational Journal of Cancer, 1996
- Urokinase receptor and colorectal cancer survivalThe Lancet, 1994