A Study of the Cardiac Stigmata in Prolonged Human Thiamine Deficiency

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Abstract
Eight clinically proved cases of prolonged thiamine deficiency were evaluated by routine pathologic study. The microscopic features were evaluated by comparison with sections of myocardium obtained from normal individuals and individuals suffering from cardiac diseases of other varieties. No specific transitory or permanent alterations were demonstrable. It is concluded that beriberi heart disease is largely the result of a reversible biochemical abnormality and is not characterized by specific pathologic lesions.

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