ROLE OF VARIOUS CEREALS IN CELIAC-DISEASE

  • 1 January 1978
    • journal article
    • research article
    • Vol. 47  (185) , 101-110
Abstract
Wheat gluten consumption produces the characteristic mucosal lesion of celiac disease in subjects who are predisposed to it, but the role of other cereals in the pathogenesis of this disease is less certain. Rye, barley, maize and rice were tested by feeding to volunteer celiac subjects [human] who had shown good mucosal recovery on a gluten free diet and assessing the effect by serial jejunal biopsy. The biopsy specimens obtained before and after challenge were compared in terms of histology and disaccharidase activity. Rye and barley were harmful, but maize and rice were harmless.

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