The relationship between nasopharyngeal carcinoma and the HL‐A system among tunisians

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Abstract
Previous reports have demonstrated an association between the HL‐A system and risk for nasopharyngeal carcinoma among the Chinese in Singapore. The present paper describes an investigation of HL‐A profiles among NPC cases and non‐NPC controls from Tunisia, to determine whether a similar association occurs in a different ethnic group. A total of 109 NPC cases and 84 controls were typed. At the second HL‐A locus the results were similar to those found in Singapore, but the effect was less marked and did not reach high statistical significance. At the first HL‐A locus, no association between A2 and NPC was found, in contrast to the Singapore results.