Serum Creatine Kinase in Acute Psychosis

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Abstract
Serum CK levels were determined in 34 acutely psychotic, 26 newly-admitted non-psychotic and 20 chronic schizophrenic patients. In each group a positively skewed distribution of CK levels was found, with no overall significant difference. Five acutely psychotic patients had levels greater than 100 I.U./L. It is argued that these `raised' levels are related to non-specific factors and do not reflect the psychotic illness directly, as has been suggested by others. Experience in this study does not support the view that serum CK estimation is of diagnostic value in psychiatric patients.