In vivo He-3 MR images of guinea pig lungs.
- 1 June 1996
- journal article
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 199 (3) , 867-870
- https://doi.org/10.1148/radiology.199.3.8638019
Abstract
The authors imaged the lungs of live guinea pigs with hyperpolarized (HP) helium-3 as a magnetic resonance (MR) signal source. HP He-3 gas produced through spin exchange with rubidium metal vapor was delivered through an MR-compatible, small-animal ventilator. Two- and three-dimensional lung images acquired with ventilation-gated, radial k-space sampling showed complete ventilation of both lungs. All images were of high quality, demonstrating that HP He-3 allows high-signal-intensity MR imaging in living systems.Keywords
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