Lesional Keratinocytes Express OKM5, Leu-8 and Leu-11b Antigens in Lichen planus
- 1 January 1988
- journal article
- research article
- Published by S. Karger AG in Dermatology
- Vol. 177 (3) , 152-158
- https://doi.org/10.1159/000248534
Abstract
Biopsy specimens of involved and uninvolved skin were studied in 16 patients with lichen planus using murine monoclonal antibodies against several cell surface markers of effector and/or accessory cells of the immune system. In contrast to uninvolved skin, keratinocytes were found to express HLA-DR, OKM5, Leu-8 and Leu-11b antigens in all biopsies from involved skin. We demonstrate here for the first time the in vivo expression of several effector and/or accessory cell markers on keratinocytes in lichen planus.Keywords
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