CLINICAL VENTILATION IMAGING WITH IN-113M AEROSOL - A COMPARISON WITH KR-81M

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  • 1 January 1982
    • journal article
    • research article
    • Vol. 23  (4) , 306-314
Abstract
Following routine ventilation (81mKr)/perfusion (99mTc) scanning, aerosol ventilation scans were obtained using a solution of 113MIn albumin and a settling-bag system. The large-volume settling bag reduces deposition of particles in the large airway by removing large droplets. The patient inhales the aerosol with 5-10 min of tidal breathing, then lung scans are obtained on a .gamma.-camera. The energy of 113MIn allows the ventilation scanning to be performed after 99mTc perfusion scanning. Semiquantitative scoring of regional ventilation showed a close correlation (r = 0.97) between 81mKr and 113In aerosol ventilation scans. The aerosol technique gave a slight underestimation of ventilation compared with 81mKr. This is explained by a slightly reduced penetration of particles to the periphery of the lung in patients with severe obstructive airways disease. In all cases the aerosol did visualize all ventilated regions. Apparently, this readily available aerosol technique can be useful for clinical ventilation imaging in multiple views.