Heartburn Requiring Frequent Antacid Use May Indicate Significant Illness
Open Access
- 23 November 1998
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1960)
- Vol. 158 (21) , 2373-2376
- https://doi.org/10.1001/archinte.158.21.2373
Abstract
ANTACIDS ARE widely used for heartburn, even though they are ineffective for many conditions associated with heartburnlike symptoms, including peptic ulcer disease and serious esophageal disease (eg, erosive gastroesophageal reflux disease [GERD], strictures, and columnar metaplasia of the esophagus (hereafter, Barrett's esophagus).1 Because heartburn may be dismissed as trivial, many affected individuals do not consult physicians and may have experienced symptoms for years.2,3 No adequate data fully characterize upper gastrointestinal tract abnormalities in regular antacid users.This publication has 7 references indexed in Scilit:
- The Diagnosis and Treatment of Gastroesophageal Reflux Disease in a Managed Care EnvironmentArchives of internal medicine (1960), 1996
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- Double-blind comparison of liquid antacid and placebo in the treatment of symptomatic reflux esophagitisDigestive Diseases and Sciences, 1983
- Columnar-lined lower esophagus: An acquired lesion with malignant predispositionThe Journal of Thoracic and Cardiovascular Surgery, 1975