Age and Lung-Histamine
Open Access
- 1 July 1947
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 56 (3) , 211-216
- https://doi.org/10.4049/jimmunol.56.3.211
Abstract
Summary: The histamine-content of foetal lungs was found to be negligible. This is in confirmation of earlier work. At birth the histamine-content of the lung is very high, the concentration being greater than that at either 8, 20 or 40 weeks. The total histamine-content of the lung varies little from birth to 8 weeks in spite of increased size of the lung, but after this period the histamine-content increases. The concentration of the lung histamine expressed as a function of the weight of the animal shows a similar distribution to that of concentration expressed as a function of the weight of the lung. The possible significance of variation in the standard deviation and means in the groups studied is discussed.Keywords
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