Glycosylated haemoglobin (HbA1c) in iron‐ and vitamin B12 deficiency
- 1 February 1990
- journal article
- research article
- Published by Wiley in Journal of Internal Medicine
- Vol. 227 (2) , 133-136
- https://doi.org/10.1111/j.1365-2796.1990.tb00131.x
Abstract
Glycosylated haemoglobin (HbA1c) was measured in 10 patients with iron deficiency anaemia, 10 patients with vitamin B12 deficiency anaemia and 10 healthy controls. Initially there were no significant differences between the groups (P > 0.4), but after treatment with iron and vitamin B12 for 3 and 6 weeks, the glycosylated haemoglobin concentration decreased significantly (P < 0.01). It was concluded that glycosylated haemoglobin is a sensitive marker of the changes in the erythrocyte population that are observed when predominantly immature erythrocytes are being produced.Keywords
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