Hypertension and the Red Cell

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Abstract
Because of their availability and ease of manipulation, red cells have long been a favorite subject for students of membrane structure and function and many transport pathways have been identified in the red cell.1 The chloride-bicarbonate exchanger, for example, is uniquely suited to the specialized role of red cells in respiration and blood buffering.2 Other, more generally distributed transport systems in red cells, such as the pumps for sodium-potassium and calcium, are vital components of almost all animal cells. Finally, red cells are capable of a host of transport activities of unknown physiologic importance: sodium-sodium exchange, lithium-sodium exchange, and sodium-potassium . . .

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