HASTENING OF AROUSAL AFTER GENERAL ANAESTHESIA WITH DOXAPRAM HYDROCHLORIDE
Open Access
- 1 May 1973
- journal article
- clinical trial
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 45 (5) , 493-496
- https://doi.org/10.1093/bja/45.5.493
Abstract
A double-blind study was undertaken to determine the effect of doxapram hydrochloride on arousal after short general anaesthesia. Of a total of forty patients, twenty were given doxapram hydrochloride at the end of anaesthesia. Doxapram injection was associated with a significantly shorter mean arousal time than was placebo. No differences in mean blood pressure or pulse rate occurred but the change in respiratory minute volume in the group given doxapram was significantly higher. No complication was observed in either group as a result of treatment.Keywords
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