PLASMA ARGININE VASOPRESSIN IN DEHYDRATED ELDERLY PATIENTS

Abstract
SUMMARY: Plasma arginine vasopressin was assessed by radioimmunoassay in dehydrated elderly patients and healthy young and elderly control subjects. The elderly control subjects' AVP levels were higher than the young control subjects (Kruskal‐Wallis rank sums z= 3.29; P z= 4.16; P <0.001) and were in the range reported to evoke a maximal antidiuretic response. It is concluded that the dehydration which often accompanies acute illness in the elderly is not primarily a consequence of inadequate AVP release.