A New Variant in the Gc System

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Abstract
An unusual Gc pattern is demonstrated in the serum of a mother and her child. Comparative studies by means of a modified immuno-electro-phoretic technique indicate that the 2 sera contain a previously undes-cribed aberrant Ge factor. Earlier studies have shown that the Gc 1 protein is heterogeneous, and in the present study the "new" factor is shown to be identical to the slow part of Gc 1. Mixtures of the "new" factor with Gc Chip in equal proportions give the same pattern as that of common Gc 1. It is proposed to call the "new" factor Gc 1C, where C stands for cathodic. The Gc types of the mother and the child of the present study should then be called Gc2-lC and Gc 1-1C respectively.