Mixed-Lineage Kinases: A Target for the Prevention of Neurodegeneration
- 10 February 2004
- journal article
- review article
- Published by Annual Reviews in Annual Review of Pharmacology and Toxicology
- Vol. 44 (1) , 451-474
- https://doi.org/10.1146/annurev.pharmtox.44.101802.121840
Abstract
The activation of the c-Jun N-terminal kinase (JNK) pathway is critical for naturally occurring neuronal cell death during development and may be important for the pathological neuronal cell death ...Keywords
This publication has 89 references indexed in Scilit:
- JNK-independent Activation of c-Jun during Neuronal Apoptosis Induced by Multiple DNA-damaging AgentsJournal of Biological Chemistry, 2003
- Identification and Characterization of a Novel MAP Kinase Kinase Kinase, MLTKJournal of Biological Chemistry, 2001
- Cloning and Expression of ZAK, a Mixed Lineage Kinase-like Protein Containing a Leucine-Zipper and a Sterile-Alpha MotifBiochemical and Biophysical Research Communications, 2000
- K‐252b Potentiation of Neurotrophin‐3 Is trkA Specific in Cells Lacking p75NTRJournal of Neurochemistry, 1997
- ErratumBiochemical and Biophysical Research Communications, 1994
- K-252b Selectively Potentiates Cellular Actions and trk Tyrosine Phosphorylation Mediated by Neurotrophin-3Journal of Neurochemistry, 1992
- Inhibition of the cellular actions of nerve growth factor by staurosporine and K252A results from the attenuation of the activity of the trk tyrosine kinaseBiochemistry, 1992
- K252a is a potent and selective inhibitor of phosphorylase kinaseBiochemical and Biophysical Research Communications, 1990
- K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinasesBiochemical and Biophysical Research Communications, 1986
- Nerve growth factor action is mediated by cyclic AMP- and Ca+2/phospholipid-dependent protein kinases.The Journal of cell biology, 1986