Capillary Electrophoresis-Fluorescence Line-Narrowing (CE-FLN) System for DNA Adduct Characterization
- 1 December 1996
- journal article
- research article
- Published by Taylor & Francis in Molecular Crystals and Liquid Crystals
- Vol. 291 (1) , 155-162
- https://doi.org/10.1080/10587259608042743
Abstract
Capillary electrophoresis (CE) interfaced with low-temperature (4.2 K) fluorescence line-narrowing (FLN) spectroscopy is used for separation and structural characterization of polycyclic aromatic hydrocarbon-derived DNA adducts. The CE-FLN system is applied to the separation and identification of mixtures of benzo[a]pyrene and dibenzo[a,l]pyrene DNA adducts. Interfacing CE with FLN spectroscopy allows on-line separation and high-resolution spectroscopic identification of CE-separated DNA adducts, providing a new powerful tool for DNA adduct structure characterization.Keywords
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