Nucleated Erythrocytes in Enriched and Unenriched Peripheral Venous Blood Samples from Pregnant and Nonpregnant Women
- 1 January 1994
- journal article
- Published by S. Karger AG in Fetal Diagnosis and Therapy
- Vol. 9 (5) , 291-295
- https://doi.org/10.1159/000263950
Abstract
The presence of nucleated erythrocytes was studied before and after enrichment with immunomagnetic beads and monoclonal antiglycophorin A (anti-GPA) antibody in the peripheral venous blood of 11 pregnant women at 10–16 weeks of gestation. Nucleated erythrocytes were identified by alkaline phosphatase antialkaline phosphatase immunostaining by means of anti-GPA antibody. In the unenriched cell samples, nucleated erythrocytes were found at frequencies of 1/2,800–1/83,000 in 6 cases. The frequency of nucleated erythrocytes was increased up to 6 times by the enrichment.Keywords
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