Small-intestinal involvement in Waldenstrom's macroglobulinemia
- 1 February 1981
- journal article
- case report
- Published by Springer Nature in Digestive Diseases and Sciences
- Vol. 26 (2) , 174-180
- https://doi.org/10.1007/bf01312238
Abstract
A patient presented with a three-year history of diarrhea and was found to have a monoclonal gammopathy (IgM lambda) and a malabsorption syndrome with dilatation of the small bowel. Small-intestinal biopsy revealed a homogeneous eosinophilic granular material between the epithelial cells. On electron microscopy this material was shown to consist of an electron-opaque background mixed wit radiolucent lipid sheres. Immunofluorescent studies showed the accellular material to consist entirely of IgM-reactive material. The patient's course and a review of the literature is presented.Keywords
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