Immunodeficiency and Elevated CD4 T Lymphocyte Counts in Two Patients Coinfected with Human Immunodeficiency Virus and Human Lymphotropic Virus Type I

Abstract
We describe two patients who were coinfected with human immunodeficiency virus (HIV) and human T-cell lymphotropic virus (HTLV) type I. They had clinical evidence of immunodeficiency (anergy, oral candidiasis, and disseminated herpes zoster) despite having elevated CD4 T lymphocyte counts (range, 2,450–5,292/mm3 ) . We conclude that CD4 lymphocyte counts may not be reliable markers of immunologic competence in patients coinfected with HIV and HTLV-I.

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