Benzodiazepine Antagonist (RO 15-1788) in Ethanol Intoxication: a Pilot Study
- 1 January 1985
- journal article
- research article
- Published by S. Karger AG in European Neurology
- Vol. 24 (5) , 352-354
- https://doi.org/10.1159/000115824
Abstract
In1983, we reported on the excellent efficacy of the benzodiazepine antagonist RO 15-1788 in cases of acute intoxication with diazepam in intensive care medicine. Upon observing a positive effect in a patient who had taken alcohol as well as diazepam a study aiming at establishing the beneficial effect of RO 15–1788 in alcoholic intoxication was started. In the meantime, we discovered a significant amelioration of the cerebral disturbance in patients suffering from hepatic coma by the same benzodiazepine antagonist. The preliminary results of a multicenter study reflecting the beneficial effect of RO 15-1788 in cases of alcohol intoxication will be presented.This publication has 1 reference indexed in Scilit:
- First Clinical Investigation of the Benzodiazepine Antagonist Ro 15-1788 in Comatose PatientsEuropean Neurology, 1983