Experiments in steroid synthesis: oestrone
- 1 January 1970
- journal article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society C: Organic
- Vol. 1 (1) , 10-18
- https://doi.org/10.1039/j39700000010
Abstract
Some work leading to syntheses of oestrone is presented. It was generally found necessary to protect the 1-carbonyl function in 5,6,7,7a-tetrahydro-8β-methylindane-1,5-dione before the introduction of alkyl groups at position 4. Alkylations of 2-methylcyclopentane-1,3-dione have been made and the results compared with similar studies on 2-methylcyclohexane-1,3-dione.Keywords
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