Hyperuricemia Due to Ethambutol
- 6 April 1972
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 286 (14) , 761-762
- https://doi.org/10.1056/nejm197204062861407
Abstract
ETHAMBUTOL has found wide clinical acceptance as an effective agent for the treatment of Mycobacterium tuberculosis infections in man. Of the recognized "side effects" associated with the administration of ethambutol, ophthalmic toxicity has received the most attention.We have found a substantial increase in the serum urate concentration in patients being treated with ethambutol. The present study was undertaken to establish the frequency, mechanism and importance of this effect in man.Materials and MethodsThe effect of prolonged therapy with ethambutol in a daily dose of 12 to 19 mg per kilogram of body weight on the metabolism of uric . . .Keywords
This publication has 2 references indexed in Scilit:
- ETHAMBUTOL IN THE RETREATMENT OF PULMONARY TUBERCULOSISAnnals of the New York Academy of Sciences, 1966
- METABOLIC AND SPECIAL STUDIES OF ETHAMBUTOL IN NORMAL VOLUNTEERS AND TUBERCULOUS PATIENTSAnnals of the New York Academy of Sciences, 1966