Abstract
The degree of differentiation of gene frequency as measured by inbreeding coefficient is obtained for the ABO and Rh blood groups in the United Kingdom. The total inbreeding coefficients in the United Kingdom for the ABO and Rh blood groups are 0.0040 and 0.0027, respectively. There are clines for the IA, IB, and IO gene frequencies on the longitude and latitude coordinates. On the other hand, there is only a cline for the D-gene frequency on the longitude in Great Britain.

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