Brain Volumes in Adult Survivors of Very Low Birth Weight: A Sibling-Controlled Study
- 1 August 2004
- journal article
- Published by American Academy of Pediatrics (AAP) in Pediatrics
- Vol. 114 (2) , 367-371
- https://doi.org/10.1542/peds.114.2.367
Abstract
Objectives. To establish whether adults who were born very low birth weight (VLBW) show altered volumes of certain brain structures. Methods. Unmatched case-control study was conducted of 33 individuals from a cohort of VLBW (Results. VLBW individuals had a 46% increase in total ventricular volume and a 17% reduction in posterior corpus callosum volume. No differences in whole brain, gray matter, or hippocampal volumes were observed. Conclusion. Specific differences exist in the volumes of certain brain structures in adults who were born VLBW compared with their normal birth weight siblings.Keywords
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