Regression of Tumors in Guinea Pigs After Treatment with Synthetic Muramyl Dipeptides and Trehalose Dimycolate
- 25 April 1980
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 208 (4442) , 415-416
- https://doi.org/10.1126/science.7189295
Abstract
A high incidence of tumor regression was observed in guinea pigs bearing transplantable, line-10 hepatocellular carcinomas when synthetic muramyl dipeptides combined with trehalose dimycolate in oil-in-water emulsions were injected directly into the tumors. These compounds are promising candidates to replace viable bacillus Calmette-Guerin in cancer immunotherapy in humans and animals.Keywords
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