Brain tumors after cranial irradiation for childhood acute lymphoblastic leukemia. A 13-year experience from the Dana-Farber cancer institute and the children's hospital
- 15 April 1987
- Vol. 59 (8) , 1506-1508
- https://doi.org/10.1002/1097-0142(19870415)59:8<1506::aid-cncr2820590819>3.0.co;2-p
Abstract
Brain tumors developed in two children after they had received cranial irradiation as central nervous system therapy for acute lymphoblastic leukemia. A review of the literature demonstrated an increased incidence of brain tumors in survivors of acute lymphoblastic leukemia who received central nervous system irradiation. Most of the brain tumors occurred within a decade after radiotherapy. Further data will be required to determine whether early post-radiation brain tumors in patients with acute lymphoblastic leukemia are due to the central nervous system irradiation or to a genetic predisposition.This publication has 21 references indexed in Scilit:
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