Abstract
The pronounced hyperglycæmia which follows decerebration at the level of the pons in rabbits may be due increased production of glucose out of glycogen, to suppression of the utilisation of glucose by the tissues or to excessive new formation of glucose (gluconeogenesis) out of protein and fat. The ascertain which of these functions is involved, we have investigated the changes in the percentages of glycogen in the liver and muscles and of lactic acid and non-protein nitrogen in the blood produced by decerebaration, and we have observed its effect on the respiratory metabolism.

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