Immunochemical characterization and serum concentrations of pregnancy-associated serum proteins in mice
- 1 March 1980
- journal article
- research article
- Published by Bioscientifica in Reproduction
- Vol. 58 (2) , 389-393
- https://doi.org/10.1530/jrf.0.0580389
Abstract
The glycoprotein structure of 2 pregnancy-associated murine proteins, .alpha.1-pyridoxamine phosphate [PAMP] and .alpha.2-PAMP, was analyzed by using concanavalin A (Con A) affinity electrophoresis; .alpha.1-PAMP was completely precipitated by free Con A, whereas .alpha.2-PAMP showed heterogeneity. The isoelectric points of .alpha.1-PAMP and .alpha.2-PAMP were 4.2 and 4.0, respectively, using crossed immunoelectrofocusing. The .alpha.2-PAMP was detectable only in the serum of pregnant mice and fetuses. Maternal serum concentrations increased from day 8 of pregnancy, remained at high values from days 14-18, and could not be detected by 2 days post partum.This publication has 4 references indexed in Scilit:
- Agarose isoelectric focusing of native human immunoglobulin M and α2-macroglobulinJournal of Immunological Methods, 1979
- Studies of pregnancy-associated murine serum proteinsReproduction, 1978
- Serology. Pregnancy-associated increase of sialoglycoprotein level in serum of normal inbred micePublished by Walter de Gruyter GmbH ,1977
- Human pregnancy-associated plasma proteins during the postpartum periodAmerican Journal of Obstetrics and Gynecology, 1976