Meiotic Maturation in Xenopus laevis Oocytes Initiated by Insulin
- 28 September 1979
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 205 (4413) , 1397-1399
- https://doi.org/10.1126/science.472755
Abstract
Insulin can induce meiotic division in Xenopus laevis oocytes. This effect shows the specificity expected of a receptor-mediated mechanism. It is potentiated by ethynylestradiol, a steroid antagonist of pregesterone (the natural hormone that provokes meiosis). The Xenopus laevis oocytes may serve as a model for the study of the poorly understood effect of insulin on cell division.Keywords
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