STRESS GASTRIC BLEEDING - PREVENTION OF EXPERIMENTAL LESIONS BY INTRAVENOUS HYPERALIMENTATION

  • 1 January 1977
    • journal article
    • research article
    • Vol. 67  (2) , 152-156
Abstract
Rats, weighing 125-150 g were restrained under a tight wire screen for 1 h at 20.degree. C of ambient temperature. Animals receiving no infusions, or those receiving an i.v. solution of normal saline, developed 16 .+-. 3 SD bleeding areas in their gastric mucosa. In animals exposed to the same degree of stress who received i.v. hyperalimentation, the number of gastric stress bleeding areas counted was 4 .+-. 2 SD. The delivery of calories and protein in the form of i.v. hyperalimentation can significantly reduce the incidence of gastric stress bleeding in an experimental model (P < .001).

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