Immunogold‐silver labeling in histology

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Abstract
Immunogold‐silver staining is a relatively new technique in light‐microscopic immunocytochemistry. It is based on silver enhancement of 1 to 10 nm gold probes immunologically bound to antigenic determinants in tissue sections. The detection efficiency of this third‐generation detection technique is compared to that of the peroxidase‐based ABC technique in routinely processed, paraffin‐embedded, human biopsy material.

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