CHRONIC COUGH, SINUSITIS, AND HYPERREACTIVE AIRWAYS IN CHILDREN - AN OFTEN OVERLOOKED ASSOCIATION

  • 1 January 1985
    • journal article
    • research article
    • Vol. 54  (3) , 195-198
Abstract
Ten patients, aged 7-16 yr, were prospectively evaluated for chronic cough of >4 mo. duration. All patients denied wheezing but in addition to cough complained of chronic obstructive nasal symptoms. Sinus roentgenograms were consistent withsinusitis in 7/10 patients. Methacholine bronchial provocation was positive in 6/9 patients. The patients were recalled for a 2 yr follow-up evaluation. Of 7 follow-up patients, bronchial asthma had developed in 3, 2 patients had chronic cough and exercise-induced bronchospasm, and 2 patients had chronic cough without wheezing. Methacholine bronchial provocation was positive in 6/6 patients. Sinus roentgenograms were compatible with sinusitis in 4/7 patients. Chronic cough in some children may be a complaint to diffuse hyperreactive airways complicated by sinusitis. In some of the children the clinical course evolved into a diffuse respiratory tract disorder including chronic obstructive eosinophilic rhinitis, recurrent or chronic sinusitis and bronchial asthma. An IgE-mediated mechanism usually could not be shown in the pathogenesis.

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