Intraictal Activation in the Neocortex: A Marker of the Epileptogenic Region
- 1 May 1994
- Vol. 35 (3) , 489-494
- https://doi.org/10.1111/j.1528-1157.1994.tb02467.x
Abstract
Summary: During the course of a seizure, subdural recordings often show secondary areas which develop in‐dependent electrographic sequences that may outlast the primary seizure sequence. We reviewed the subdural data on 8 patients with intraictal secondarily activated foci (ISF). In 6 patients, ISFs were documented to be capable of generating independent seizures; ISF seizures occurred during the initial subdural monitoring period in 3, but became ictal generators only after excision of the primary focus in the other 3. Prominent interictal abnormalities were observed at the ISFs in 5 of 8 patients. The ISF in 1 patient correlated with the structural lesion on magnetic resonance imaging (MRI) scan. We believe that ISFs have significant epileptogenicity and should be re‐sected when possible.Keywords
This publication has 14 references indexed in Scilit:
- The Role of Secondary Epileptogenesis in Human EpilepsyArchives of Neurology, 1991
- Localization of Seizure FociJournal Of Clinical Neurophysiology, 1991
- The Hans Berger lecture Functional explorations of the human epileptic brain and their therapeutic implicationsElectroencephalography and Clinical Neurophysiology, 1990
- National Institutes of Health Consensus Conference. Surgery for epilepsyPublished by American Medical Association (AMA) ,1990
- The Development of Independent Foci in Epileptic PatientsArchives of Neurology, 1990
- Varieties of Human Secondary EpileptogenesisJournal Of Clinical Neurophysiology, 1989
- The postictal electroencephalogramElectroencephalography and Clinical Neurophysiology, 1988
- Long-term Clinical and EEG Changes in Patients With EpilepsyArchives of Neurology, 1985
- Facilication and antagonism of kindled seizure development in the limbic system of the ratElectroencephalography and Clinical Neurophysiology, 1981
- Interaction of Epileptic Activities of Bilateral Deep Temporal Origin. An Experimental StudyEpilepsia, 1976