Transformations using benzyl 6-isocyanopenicillanate
- 1 January 1979
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 10,p. 2455-2467
- https://doi.org/10.1039/p19790002455
Abstract
The preparation and C-6 epimerisation of benzyl 6α-isocyanopenicillanate is described. By utilising the activating influence of the isocyanide group and a subsequent conversion of this group into an amino-group under mild conditions, 6α-substituted penicillins were thereby prepared. Additionally, several novel rearrangements of these isocyanides are described.This publication has 0 references indexed in Scilit: