Abstract
Concns. of CO2 as low as 2.5% in the inspired air of hamsters (Mesocricetus auratus) and ground squirrels (Citellus tridecemlineatus) caused an increase of respiratory rate. Ground squirrels showed concurrent increases of heart rate, but concns. above 5% CO2 were required to increase the heart rates of hamsters. It is concluded that the homeostatic mechanism of respiration remains operative during hibernation.

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