Relief of injection pain in adults EMLA cream for 5 minutes before venepuncture

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Abstract
Summary: The effectiveness of skin anaesthesia after 5 minutes’ topical application of a lignocaine‐prilocaine cream was evaluated. One hundred and twenty patients estimated the pain of antecubital venepuncture both on a linear scale and verbally after use of the cream for either 5 or 60 minutes, a placebo cream or no treatment. Reported pain was significantly less after only 5 minutes of the lignocaine‐prilocaine cream (p = 0.002). The cream can be used to relieve the pain of all routine injections.