Bilateral Deep Brain Stimulation vs Best Medical Therapy for Patients With Advanced Parkinson DiseaseA Randomized Controlled Trial
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Open Access
- 7 January 2009
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 301 (1) , 63-73
- https://doi.org/10.1001/jama.2008.929
Abstract
Deep brain stimulation is the surgical intervention of choice when Parkinson disease (PD) motor complications are inadequately managed with medications. Ideal candidates have fluctuating motor symptoms or medication-related adverse effects, few comorbidities, and no cognitive or behavioral disorders.1 This younger, healthier population reflects a selection bias observed in most deep brain stimulation studies.2,3 The typical patient with PD is older and has other medical conditions.Keywords
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