Ewing's Sarcoma and Peripheral Primitive Neuroectodermal Tumor: An Interim Report
- 1 October 1996
- journal article
- research article
- Published by SAGE Publications in Annals of Otology, Rhinology & Laryngology
- Vol. 105 (10) , 838-843
- https://doi.org/10.1177/000348949610501014
Abstract
The primitive neuroectoderm and its progeny seemingly give rise to an ever-increasing number of clinicopathologic entities. Ewing's sarcoma and peripheral primitive neuroectodermal tumor have recently been united by relatively unique antigens expressed by the MIC-2 gene, commonly coexpressed neural markers, and cytogenetic and molecular genetic abnormalities. Because of these factors, the current thinking is that Ewing's sarcoma and the peripheral primitive neuroectodermal tumor are parts of a phenotypic spectrum. We present an “interim report” on this group of neoplasms, emphasizing their presentation in the head and neckKeywords
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